Octreotide Acetate

Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.

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CAT#10-101-26
ExplanationOctreotide is a somatostatin analog that binds to the somatostatin receptor, mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production.
Synonyms/AliasSMS 201-995
M.F/FormulaC49H66N10O10S2
M.W/Mr.1019.24
SequenceThree Letter Code: H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol acetate salt (Disulfide bond)
ApplicationOctreotide is used for the treatment of growth hormone producing tumors and bleeding esophageal varices. It is also used in nuclear medicine imaging by labelling with indium-111.
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