[Pyr-5] Substance P (5-11) is a pyroglutamyl-modified fragment representing the central region of substance P. The N-terminal cyclization stabilizes the peptide and alters charge properties. Retention of core hydrophobic and basic residues preserves receptor-interacting elements. Researchers employ it to dissect tachykinin receptor recognition using well-defined short sequences.
CAT No: S09051
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