Selepressin

Name: Selepressin
Brand: Creative Peptides
SKU: 10-101-173
Availability: MadeToOrder

Selepressin (INN), also known as [Phe(2),Ile(3), Hgn(4),Orn(iPr)(8)]vasopressin) is a potent, highly selective, short-acting peptide full agonist of the vasopressin 1A receptor and analog of vasopressin which is under development by Ferring Pharmaceuticals for the treatment of vasodilatory hypotension in septic shock.

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CAT No: 10-101-173

CAS No: 876296-47-8

Synonyms/Alias: SELEPRESSIN;Fe202158;876296-47-8;Fe 202158;Selepressin [USAN:INN];Selepressin [INN];UNII-8P2T76M0SJ;selepresina;selepressine;8P2T76M0SJ;FE-202158;(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-10-(4-amino-4-oxobutyl)-7-(2-amino-2-oxoethyl)-16-benzyl-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-5-(propan-2-ylamino)pentan-2-yl]pyrrolidine-2-carboxamide;SELEPRESSIN [USAN];SELEPRESSIN [WHO-DD];Glycinamide, L-cysteinyl-L-phenylalanyl-L-isoleucyl-6-oxo-L-lysyl-L-asparaginyl-L-cysteinyl-L-prolyl-n5-(1-methylethyl)-L-ornithyl-, cyclic (1-6)-disulfide;CHEMBL1817709;DTXSID90236538;(2-L-PHENYLALANINE,3-L-ISOLEUCINE,4-(6-OXO-L-LYSINE), 8-(5-N-(PROPAN-2-YL)-L-ORNITHINE))HUMAN VASOPRESSIN;selepressinum;(2S)-1-((4R,7S,10S,13S,16S,19R)-19-amino-10-(4-amino-4-oxobutyl)-7-(2-amino-2-oxoethyl)-16-benzyl-13-((2S)-butan-2-yl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl)-N-((2S)-1-((2-amino-2-oxoethyl)amino)-1-oxo-5-(propan-2-ylamino)pentan-2-yl)pyrrolidine-2-carboxamide;SCHEMBL19712230;GTPL11454;DTXCID20159029;BDBM50350870;DB12495;HY-105239;CS-0025461;Q21098876;

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M.F/Formula	C46H73N13O11S2
M.W/Mr.	1048.3
Sequence	One Letter Code:CFIXNCPXG Three Letter Code:H-Cys(1)-Phe-Ile-hGln-Asn-Cys(1)-Pro-Orn(iPr)(iPr)-Gly-NH2
Labeling Target	Arginine Vasopressin Receptor 1A
Application	Selepressin is deveolped for the treatment of vasodilatory hypotension in septic shock.
Appearance	Solid powder
Purity	>98% (or refer to the Certificate of Analysis)
Activity	Agonist
Biological Activity	Selepressin, also known as FE-202158, is a potent, selective vasopressin V1a receptor agonist potentially for the treatment of septic shock.
Areas of Interest	Septic shock
Functions	Type 1 angiotensin receptor binding
Target	Vasopressin Receptor

Source#	Synthetic
Long-term Storage Conditions	Soluble in DMSO.
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Short-term Storage Conditions	Dry, dark and at 0 - 4 °C
Solubility	-20 °C
Organism	Human
InChI	InChI=1S/C46H73N13O11S2/c1-5-26(4)38-45(69)54-30(14-9-17-35(48)60)41(65)56-32(21-36(49)61)42(66)57-33(24-72-71-23-28(47)39(63)55-31(43(67)58-38)20-27-12-7-6-8-13-27)46(70)59-19-11-16-34(59)44(68)53-29(15-10-18-51-25(2)3)40(64)52-22-37(50)62/h6-8,12-13,25-26,28-34,38,51H,5,9-11,14-24,47H2,1-4H3,(H2,48,60)(H2,49,61)(H2,50,62)(H,52,64)(H,53,68)(H,54,69)(H,55,63)(H,56,65)(H,57,66)(H,58,67)/t26-,28-,29-,30-,31-,32-,33-,34-,38-/m0/s1
InChI Key	JCVQBJTWWDYUFQ-MRUTUVJXSA-N
ShelfLife	>2 years if stored properly

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