Selepressin
Selepressin (INN), also known as [Phe(2),Ile(3), Hgn(4),Orn(iPr)(8)]vasopressin) is a potent, highly selective, short-acting peptide full agonist of the vasopressin 1A receptor and analog of vasopressin which is under development by Ferring Pharmaceuticals for the treatment of vasodilatory hypotension in septic shock.
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| CAT# | 10-101-173 |
| CAS | 876296-47-8 |
| Synonyms/Alias | (Phe2;Ile3;Hgn4;Orn(iPr)8)vasopressin;2-Phe-3-Ile-4-Hgn-8-Orn(iPr)-vasopressin; FE 202158;vasopressin; Phe(2)-Ile(3)-Hgn(4)-Orn(iPr)(8)-;vasopressin; phenylalanyl(2)-isoleucyl(3)-Hgn(4)-ornithyl(isopropyl)(8)- |
| M.F/Formula | C46H73N13O11S2 |
| M.W/Mr. | 1048.28232 |
| Sequence | H-Cys(1)-Phe-Ile-Nva(CONH2)-Asn-Cys(1)-Pro-Orn(iPr)-Gly-NH2 |
| Labeling Target | Arginine Vasopressin Receptor 1A |
| Application | Selepressin is deveolped for the treatment of vasodilatory hypotension in septic shock. |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Activity | Agonist |
| Biological Activity | Selepressin, also known as FE-202158, is a potent, selective vasopressin V1a receptor agonist potentially for the treatment of septic shock. |
| Areas of Interest | Septic shock |
| Functions | Type 1 angiotensin receptor binding |
| Disease | Hereditary angioneurotic edema |
| Target | Vasopressin Receptor |
| Source# | Synthetic |
Storage | -20°C |
Solubility | Soluble in DMSO. |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Short-term Storage Conditions | Dry, dark and at 0 - 4 °C |
Long-term Storage Conditions | -20 °C |
Organism | Human |
ShelfLife | >2 years if stored properly |
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