Tosyl-L-glutamic acid is a protected L-glutamic acid derivative in which the α-amino group is sulfonylated with a tosyl (p-toluenesulfonyl) protecting group, yielding a glutamate-based amino acid building block with a side-chain carboxylic acid. The molecule contains a free carboxyl group at the α-position and an additional carboxyl group on the γ-side chain, while the tosyl-protected amino functionality reduces undesired amine reactivity during chemical transformations and preserves the acidic side-chain for controlled handling. Tosyl-L-glutamic acid is used in peptide and amino acid synthesis workflows as a precursor that supports chemoselective coupling at protected versus deprotected functional groups, and it also serves as a defined glutamate analogue for structure-reactivity studies and analytical method development involving glutamic acid functional motifs.
CAT No: CP00739
CAS No:4816-80-2
Synonyms/Alias:4816-80-2;(S)-2-(4-Methylphenylsulfonamido)pentanedioicacid;Tosyl-L-glutamicacid;N-(p-Tolylsulphonyl)-L-glutamicacid;SBB006582;TOS-GLU-OH;N-Tosyl-L-glutamicacid;AC1M14DX;KSC493E0F;SCHEMBL255603;(+)-N-Tosyl-L-glutamicacid;ARK087;CTK3J3202;KKOZKXBAPIYWAT-JTQLQIEISA-N;MolPort-004-947-065;ACN-S002624;ZINC2566280;6602AB;(+)-toluene-p-sulphonylglutamicacid;AKOS010386362;AM81727;N-(p-Toluenesulfonyl)-L-glutamicacid;RL03797;AJ-41268;AK112276
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