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Z-Arg-AMC

Z-Arg-AMC contains an L-arginine-derived side chain linked to the aminomethylcoumarin (AMC) fluorophore, making it an arginine-based amino acid derivative designed for substrate-like behavior in protease assays. The molecule bears an N-terminal benzyloxycarbonyl (Z, Cbz) protecting group on the amino functionality and presents the arginine guanidinium side chain, while the AMC moiety provides an amide-linked fluorogenic reporter. In biochemical and analytical workflows, Z-Arg-AMC is used as a fluorogenic substrate to monitor cleavage events by observing changes associated with release or transformation of the AMC reporter, supporting enzyme activity studies and assay development.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP27277

CAS No:62037-44-9

Synonyms/Alias:BPOC-THR(TBU)-OSU;62020-53-5;6467AH;KM0567;ZINC71788263

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  • CMC information required for an IND
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M.F/Formula
C28H34N2O7
M.W/Mr.
465.51
Size
250 mg;1 g;
InChI
1S/C28H34N2O7/c1-18(35-27(2,3)4)24(25(33)37-30-22(31)16-17-23(30)32)29-26(34)36-28(5,6)21-14-12-20(13-15-21)19-10-8-7-9-11-19/h7-15,18,24H,16-17H2,1-6H3,(H,29,34)/t18-,24+/m1/s1
InChI Key
SSETYDOAFGWCOY-KOSHJBKYSA-N
Canonical SMILES
CC(C(C(=O)ON1C(=O)CCC1=O)NC(=O)OC(C)(C)C2=CC=C(C=C2)C3=CC=CC=C3)OC(C)(C)C

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