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Z-D-Norleucine

Z-D-Norleucine is a protected, non-proteinogenic amino acid derivative in which the amino group of D-norleucine is carbobenzyloxy (benzyloxycarbonyl, Z/Cbz) protected, yielding a Z-protected amino acid suitable for peptide chemistry. The molecule retains the free carboxyl group and features a straight-chain aliphatic side chain characteristic of norleucine, with stereochemistry specified as D at the α-carbon while the N-terminus is masked by the Z protecting group to reduce undesired amine reactivity. Z-D-Norleucine is used as a building block for controlled incorporation of a norleucine residue into peptide chains and as a protected intermediate for stepwise synthesis and chemical labeling workflows where orthogonal handling of the amino functionality is required.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP08509

CAS No:15027-14-2

Synonyms/Alias:15027-14-2;N-Benzyloxycarbonyl-D-Norleucine;(R)-2-(((Benzyloxy)carbonyl)amino)hexanoicacid;Z-D-norleucine;Z-D-Nle-OH;SBB028584;AC1OCXCS;SCHEMBL11332452;CTK3J4726;MolPort-003-939-978;ZINC2168263;7523AA;ANW-58108;MFCD00063169;(+)-N-Benzyloxycarbonyl-D-norleucine;AM82591;AJ-33836;AK-87805;RT-002163;FT-0697726;K-4778;(2R)-2-(phenylmethoxycarbonylamino)hexanoicacid;(2R)-2-[(phenylmethoxy)carbonylamino]hexanoicacid

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M.F/Formula
C14H19NO4
M.W/Mr.
265.3
Abbr
Z-D-Nle-OH
InChI
1S/C14H19NO4/c1-2-3-9-12(13(16)17)15-14(18)19-10-11-7-5-4-6-8-11/h4-8,12H,2-3,9-10H2,1H3,(H,15,18)(H,16,17)/t12-/m1/s1
InChI Key
NMYWMOZOCYAHNC-GFCCVEGCSA-N
Canonical SMILES
CCCCC(C(=O)O)NC(=O)OCC1=CC=CC=C1

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