Z-L-aspartic acid α-methyl ester

Z-L-aspartic acid α-methyl ester is a protected L-aspartic acid derivative in which the α-carboxyl group is esterified as a methyl ester while the amino functionality is protected with a benzyloxycarbonyl (Z, Cbz) group, yielding an aspartate-based amino acid ester. The molecule contains a side-chain carboxylic acid characteristic of aspartic acid, alongside the esterified α-carboxyl and the carbamate-protected α-amino group, with stereochemistry specified as L at the α-carbon. Z-L-aspartic acid α-methyl ester is used as a building block for peptide and amino-acid derivative synthesis, where the Z group helps control chemoselectivity during stepwise coupling and the α-methyl ester provides a defined protected ester handle for downstream transformations or incorporation into larger peptide structures.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP00428

CAS No:4668-42-2

Synonyms/Alias:Z-Asp-OMe;4668-42-2;Cbz-Asp-OMe;(S)-3-(((Benzyloxy)carbonyl)amino)-4-methoxy-4-oxobutanoicacid;Z-L-Asparticacid1-methylester;N-Cbz-L-asparticacidalpha-methylester;Z-L-Asp-OMe;PubChem18988;AC1ODW3Y;AC1Q41IB;1-MethylN-Cbz-L-aspartate;95998_ALDRICH;SCHEMBL1067460;(3S)-3-{[(BENZYLOXY)CARBONYL]AMINO}-4-METHOXY-4-OXOBUTANOICACID;95998_FLUKA;MFFFBNAPQRDRQW-JTQLQIEISA-N;MolPort-001-794-455;Z-L-asparticacid|A-methylester;ZINC2575025;1-MethylN-Carbobenzoxy-L-aspartate;CZ-083;MFCD00083277;SBB064263;AKOS015889948;AM81615

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M.F/Formula
C13H15NO6
M.W/Mr.
281.3
Abbr
Z-Asp-OMe
InChI
1S/C13H15NO6/c1-19-12(17)10(7-11(15)16)14-13(18)20-8-9-5-3-2-4-6-9/h2-6,10H,7-8H2,1H3,(H,14,18)(H,15,16)/t10-/m0/s1
InChI Key
MFFFBNAPQRDRQW-JTQLQIEISA-N
Canonical SMILES
COC(=O)C(CC(=O)O)NC(=O)OCC1=CC=CC=C1

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