Z-L-serine

Name: Z-L-serine
Brand: Creative Peptides
Rating: 5 (1 reviews)

Z-L-serine contains the L-serine amino acid framework bearing a side-chain hydroxymethyl group (-CH2OH) and both amino and carboxyl functionality, with the amino group protected as a benzyloxycarbonyl (Z, Cbz) carbamate. The molecule is a protected amino acid derivative in which the Z group masks the α-amino functionality to control chemoselectivity during peptide coupling while the free carboxyl group remains available for activation and subsequent bond formation. Z-L-serine is used as a building block for peptide synthesis and related amino acid derivative preparation where stepwise assembly and protection of the amine are required to minimize side reactions.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP01827

CAS No:1145-80-8

Synonyms/Alias:N-Cbz-L-serine;Z-Ser-OH;1145-80-8;Carbobenzyloxy-L-serine;Z-L-Serine;Cbz-L-Ser-OH;N-Carbobenzyloxy-L-serine;N-Benzyloxycarbonyl-L-serine;Benzyloxycarbonylserine;N-Carbobenzoxy-L-serine;CBZ-L-SERINE;CHEMBL1222399;GNIDSOFZAKMQAO-VIFPVBQESA-N;ST50307080;(2S)-3-hydroxy-2-(phenylmethoxycarbonylamino)propanoicacid;(2S)-3-Hydroxy-2-[(phenylmethoxy)carbonylamino]propanoicacid;(S)-2-(BENZYLOXYCARBONYLAMINO)-3-HYDROXYPROPANOICACID;CBZ-SER-OH;N-[(Benzyloxy)carbonyl]serine;(2S)-2-{[(benzyloxy)carbonyl]amino}-3-hydroxypropanoicacid;(2S)-2-([(BENZYLOXY)CARBONYL]AMINO)-3-HYDROXYPROPANOICACID;CBZ-serine;L-Serine,N-[(phenylmethoxy)carbonyl]-;N-carbobenzyloxyserine;N-carbobenzyloxy-serine

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.F/Formula

C11H13NO5

M.W/Mr.

239.2

Abbr

Z-Ser-OH

InChI

1S/C11H13NO5/c13-6-9(10(14)15)12-11(16)17-7-8-4-2-1-3-5-8/h1-5,9,13H,6-7H2,(H,12,16)(H,14,15)/t9-/m0/s1

InChI Key

GNIDSOFZAKMQAO-VIFPVBQESA-N

Canonical SMILES

C1=CC=C(C=C1)COC(=O)NC(CO)C(=O)O

1. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists

2. Oleic acid and glucose regulate glucagon-like peptide 1 receptor expression in a rat pancreatic ductal cell line

3. Crystal Structure of BamB from Pseudomonas aeruginosa and Functional Evaluation of Its Conserved Structural Features

4. High fat diet and GLP-1 drugs induce pancreatic injury in mice

5. Genetic, cellular, and structural characterization of the membrane potential-dependent cell-penetrating peptide translocation pore

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