Z-O-tert.butyl-L-threonine benzyl ester is a protected threonine derivative in which the threonine alpha-amino group is carbamate-protected as a benzyloxycarbonyl (Z) group, and the carboxyl group is esterified as a benzyl ester while the side-chain hydroxyl is masked as a tert-butyl ether (O-tert-butyl). The molecule therefore contains a Z-protected amino functionality and an O-tert-butyl-protected secondary alcohol on the threonine side chain, with the L stereochemical designation retained from the parent amino acid. In peptide and amino acid synthesis workflows, this protected amino acid ester functions as a stepwise building block in which the orthogonal protecting groups help control chemoselectivity during coupling and subsequent deprotection steps, while the benzyl ester and tert-butyl ether provide handles for orthogonal removal to access the free carboxylate and side-chain hydroxyl.
CAT No: CP01928
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