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Z-p-fluoro-Phe-OH

Z-p-fluoro-Phe-OH is a protected phenylalanine derivative in which the amino group is masked by a Z (benzyloxycarbonyl, Cbz) protecting group and the aromatic side chain bears a para-fluoro substituent. The molecule contains a free carboxylic acid (-COOH) and a protected carbamate-type nitrogen, with the p-fluorophenyl side chain providing a fluorinated aromatic functionality while the stereocenter at the amino acid backbone follows the configuration implied by the supplied name. Z-p-fluoro-Phe-OH is used as a building block for stepwise peptide synthesis and for structure-activity or labeling studies where incorporation of a fluorinated phenylalanine analogue is required to probe effects of aromatic fluorination on peptide properties.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP26529

CAS No:17543-58-7

Synonyms/Alias:Z-4-Fluoro-Phe-OH;17543-58-7;(S)-2-(((Benzyloxy)carbonyl)amino)-3-(4-fluorophenyl)propanoicacid;Z-Phe(4-F)-OH;117467-73-9;Cbz-4-fluoro-L-Phe;Cbz-L-Phe(4-F)-OH;Cbz-4-Fluoro-L-Phenylalanine;SCHEMBL2511842;MolPort-003-990-176;ZINC2561190;9190AA;CZ-085;AJ-40684;AK-49493;KB-48786;KB-210844;FT-0696200;ST24035808;A00216;K-5406;M03203;N-(Benzyloxycarbonyl)-4-fluoro-L-phenylalanine;N-[(Benzyloxy)carbonyl]-4-fluoro-L-phenylalanine;J-300407

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M.F/Formula
C17H16FNO4
M.W/Mr.
317.32
Size
1 g;5 g;
InChI
1S/C17H16FNO4/c18-14-8-6-12(7-9-14)10-15(16(20)21)19-17(22)23-11-13-4-2-1-3-5-13/h1-9,15H,10-11H2,(H,19,22)(H,20,21)/t15-/m0/s1
InChI Key
YJSNXFAVHKHBPV-HNNXBMFYSA-N
Canonical SMILES
C1=CC=C(C=C1)COC(=O)NC(CC2=CC=C(C=C2)F)C(=O)O

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