Z-1,2-trans-ACHC-OH

Name: Z-1,2-trans-ACHC-OH
Brand: Creative Peptides
Rating: 5 (1 reviews)

Z-1,2-trans-ACHC-OH is a protected, non-proteinogenic amino acid derivative featuring an ACHC (1-aminocyclohexane carboxylic acid) core with a defined 1,2-trans relationship across the adjacent stereocenters and a Z-configured substituent consistent with a Z-protecting group designation. The molecule contains a free carboxylic acid functional group and an amino functionality while bearing the Z-type protecting group that modulates chemoselectivity by reducing undesired side reactions of the amine during handling and coupling chemistry. Z-1,2-trans-ACHC-OH is used as a building block in peptide and peptidomimetic synthesis and in structure-activity or stereochemical studies where a cyclohexyl-based, conformationally constrained amino acid scaffold is required for controlled incorporation into larger amide frameworks.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25943

CAS No:61935-48-6

Synonyms/Alias:61925-78-8;Boc-S-4-methylbenzyl-D-cysteine;Boc-D-Cys(4-Mbzl)-OH;(S)-2-((tert-Butoxycarbonyl)amino)-3-((4-methylbenzyl)thio)propanoicacid;AmbotzBAA5420;AC1Q2M2G;Boc-D-Cys(4-MeBzl)-OH;BOC-D-CYS(MBZL)-OH;SCHEMBL7331137;MolPort-005-938-123;ZINC1576253;KM0556;AM81659;AC-19261;AJ-27317;AK-81104;KB-48408;X5770;(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-{[(4-methylphenyl)methyl]sulfanyl}propanoicacid

Chemical Name:trans-1-(Benzyloxycarbonyl-amino)-cyclohexyl-2-carboxylic acid

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cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.F/Formula

C16H23NO4S

M.W/Mr.

277,32 g/mole

Size

1 g;5 g;25 g;

InChI

1S/C16H23NO4S/c1-11-5-7-12(8-6-11)9-22-10-13(14(18)19)17-15(20)21-16(2,3)4/h5-8,13H,9-10H2,1-4H3,(H,17,20)(H,18,19)/t13-/m1/s1

InChI Key

CUNVVZWSABRKAL-CYBMUJFWSA-N

Canonical SMILES

CC1=CC=C(C=C1)CSCC(C(=O)O)NC(=O)OC(C)(C)C

1. Myotropic activity of allatostatins in tenebrionid beetles

2. Quantitative Analysis of Ligands Effects on Bioefficacy of Nanoemulsion encapsulating Depigmenting Active

3. Peptides as Active Ingredients: A Challenge for Cosmeceutical Industry

4. A possible role of tachykinin-related peptide on an immune system activity of mealworm beetle, Tenebrio molitor L

5. GLP-1, exendin-4 and C-peptide regulate pancreatic islet microcirculation, insulin secretion and glucose tolerance in rats

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