Neuropeptide FF

Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, interacts with two distinct G-protein-coupled receptors, NPFF(1) and NPFF(2) and has wide variety of physiological functions in the brain including central cardiovascular and neuroendocrine regulation.

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Neuropeptide FF(CAS 99566-27-5)

CAT No: R1542

CAS No: 99566-27-5

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Synonyms/AliasNeuropeptide FF;99566-27-5;NPFF;MFCD00076704;CHEMBL429731;phe-leu-phe-gln-pro-gln-arg-phe-amide;PrRP31;NPSF;Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe amide;[125I]-neuropeptide FF;Neuropeptide ff(cattle)(9ci);[125I]NPFF;GTPL3797;[125I]-NPFF;BDBM86139;HY-P1248;BDBM50037557;AKOS024457451;NCGC00167257-01;DA-66042;MS-31938;CAS_99566-27-5;CAS_235433-36-0;CS-0029121;Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2;Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe amide, >=95% (HPLC);(2S)-2-[[(2S)-1-[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide;2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-3-phenyl-propionylamino}-4-carbamoyl-butyryl)-pyrrolidine-2-carbonyl]-amino}-pentanedioic acid 5-amide 1-{[1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butyl]-amide};
M.F/FormulaC54H76N14O10
M.W/Mr.1081.3
SequenceOne Letter Code:FLFQPQRF
Three Letter Code:H-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2
Source#Synthetic
InChIInChI=1S/C54H76N14O10/c1-32(2)28-41(66-47(72)36(55)29-33-14-6-3-7-15-33)50(75)67-42(31-35-18-10-5-11-19-35)51(76)64-39(23-25-45(57)70)53(78)68-27-13-21-43(68)52(77)63-38(22-24-44(56)69)49(74)62-37(20-12-26-61-54(59)60)48(73)65-40(46(58)71)30-34-16-8-4-9-17-34/h3-11,14-19,32,36-43H,12-13,20-31,55H2,1-2H3,(H2,56,69)(H2,57,70)(H2,58,71)(H,62,74)(H,63,77)(H,64,76)(H,65,73)(H,66,72)(H,67,75)(H4,59,60,61)/t36-,37-,38-,39-,40-,41-,42-,43-/m0/s1
InChI KeyHWYCFZUSOBOBIN-AQJXLSMYSA-N

1. Exosomes-mediated Transfer of miR-125a/b in Cell-to-cell Communication: A Novel Mechanism of Genetic Exchange in the Intestinal Microenvironment

2. High fat diet and GLP-1 drugs induce pancreatic injury in mice

3. Therapeutic potential of an intestinotrophic hormone, glucagon-like peptide 2, for treatment of type 2 short bowel syndrome rats with intestinal bacterial and fungal dysbiosis

4. Identification, Localization in the Central Nervous System and Novel Myostimulatory Effect of Allatostatins in Tenebrio molitor Beetle

5. Olfactory receptor based piezoelectric biosensors for detection of alcohols related to food safety applications

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