Neuropeptide FF

Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, interacts with two distinct G-protein-coupled receptors, NPFF(1) and NPFF(2) and has wide variety of physiological functions in the brain including central cardiovascular and neuroendocrine regulation.

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CAT No: R1542

CAS No: 99566-27-5

Synonyms/Alias: Neuropeptide FF;99566-27-5;NPFF;MFCD00076704;CHEMBL429731;phe-leu-phe-gln-pro-gln-arg-phe-amide;PrRP31;NPSF;Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe amide;[125I]-neuropeptide FF;Neuropeptide ff(cattle)(9ci);[125I]NPFF;GTPL3797;[125I]-NPFF;BDBM86139;HY-P1248;BDBM50037557;AKOS024457451;NCGC00167257-01;DA-66042;MS-31938;CAS_99566-27-5;CAS_235433-36-0;CS-0029121;Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2;Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe amide, >=95% (HPLC);(2S)-2-[[(2S)-1-[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide;2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-3-phenyl-propionylamino}-4-carbamoyl-butyryl)-pyrrolidine-2-carbonyl]-amino}-pentanedioic acid 5-amide 1-{[1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butyl]-amide};

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C54H76N14O10
M.W/Mr.	1081.3
Sequence	One Letter Code:FLFQPQRF Three Letter Code:H-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2

Source#	Synthetic
InChI	InChI=1S/C54H76N14O10/c1-32(2)28-41(66-47(72)36(55)29-33-14-6-3-7-15-33)50(75)67-42(31-35-18-10-5-11-19-35)51(76)64-39(23-25-45(57)70)53(78)68-27-13-21-43(68)52(77)63-38(22-24-44(56)69)49(74)62-37(20-12-26-61-54(59)60)48(73)65-40(46(58)71)30-34-16-8-4-9-17-34/h3-11,14-19,32,36-43H,12-13,20-31,55H2,1-2H3,(H2,56,69)(H2,57,70)(H2,58,71)(H,62,74)(H,63,77)(H,64,76)(H,65,73)(H,66,72)(H,67,75)(H4,59,60,61)/t36-,37-,38-,39-,40-,41-,42-,43-/m0/s1
InChI Key	HWYCFZUSOBOBIN-AQJXLSMYSA-N

1. GLP-1, exendin-4 and C-peptide regulate pancreatic islet microcirculation, insulin secretion and glucose tolerance in rats

2. Identification, Localization in the Central Nervous System and Novel Myostimulatory Effect of Allatostatins in Tenebrio molitor Beetle

3. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment

4. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate

5. Emu oil in combination with other active ingredients for treating skin imperfections

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Neuropeptide FF

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