Neuropeptide FF

Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, interacts with two distinct G-protein-coupled receptors, NPFF(1) and NPFF(2) and has wide variety of physiological functions in the brain including central cardiovascular and neuroendocrine regulation.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Neuropeptide FF(CAS 99566-27-5)

CAT No: R1542

CAS No:99566-27-5

Synonyms/Alias:Neuropeptide FF;99566-27-5;NPFF;MFCD00076704;CHEMBL429731;phe-leu-phe-gln-pro-gln-arg-phe-amide;PrRP31;NPSF;Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe amide;[125I]-neuropeptide FF;Neuropeptide ff(cattle)(9ci);[125I]NPFF;GTPL3797;[125I]-NPFF;BDBM86139;HY-P1248;BDBM50037557;AKOS024457451;NCGC00167257-01;DA-66042;MS-31938;CAS_99566-27-5;CAS_235433-36-0;CS-0029121;Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2;Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe amide, >=95% (HPLC);(2S)-2-[[(2S)-1-[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide;2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-3-phenyl-propionylamino}-4-carbamoyl-butyryl)-pyrrolidine-2-carbonyl]-amino}-pentanedioic acid 5-amide 1-{[1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butyl]-amide};

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C54H76N14O10
M.W/Mr.
1081.3
Sequence
One Letter Code:FLFQPQRF
Three Letter Code:H-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2
Source#
Synthetic
InChI
InChI=1S/C54H76N14O10/c1-32(2)28-41(66-47(72)36(55)29-33-14-6-3-7-15-33)50(75)67-42(31-35-18-10-5-11-19-35)51(76)64-39(23-25-45(57)70)53(78)68-27-13-21-43(68)52(77)63-38(22-24-44(56)69)49(74)62-37(20-12-26-61-54(59)60)48(73)65-40(46(58)71)30-34-16-8-4-9-17-34/h3-11,14-19,32,36-43H,12-13,20-31,55H2,1-2H3,(H2,56,69)(H2,57,70)(H2,58,71)(H,62,74)(H,63,77)(H,64,76)(H,65,73)(H,66,72)(H,67,75)(H4,59,60,61)/t36-,37-,38-,39-,40-,41-,42-,43-/m0/s1
InChI Key
HWYCFZUSOBOBIN-AQJXLSMYSA-N

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