Steroid Receptor Coactivator-1, SRC-1 (686-700)

This peptide is amino acids 686 to 700 fragment containing the second LXXLL motif, derived from NR box II of steroid receptor coactivator (SRC1). Coactivator proteins interact with nuclear receptors in a ligand-dependent manner and augment transcription.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: X21202

Custom Peptide Synthesis

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.W/Mr.

1771.1

Sequence

One Letter Code: RHKILHRLLQEGSPS
Three Letter Code: H-Arg-His-Lys-Ile-Leu-His-Arg-Leu-Leu-Gln-Glu-Gly-Ser-Pro-Ser-OH

References

1. Urizar, N. et al. Science 296, 1703 (2002);
2. Parks, D. et al. Science 284, 1365 (1999).

1. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

2. Oleic acid and glucose regulate glucagon-like peptide 1 receptor expression in a rat pancreatic ductal cell line

3. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate

4. Glucagonlike peptide 2 analogue teduglutide: stimulation of proliferation but reduction of differentiation in human Caco-2 intestinal epithelial cells

5. Relatedness of antibodies to peptides containing homocitrulline or citrulline in patients with rheumatoid arthritis

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